REJUVENATION OF A BODY: DISCOVERY LEADING TO THE DRASTIC CHANGES OF GERONTOLOGY OPPORTUNITIES (REVIEW OF PERSONAL RESEARCHES)

  • Volodymyr Monastyrskyi Danylo Halytskyi Lviv National Medical University, Lviv, Ukraine
Keywords: lifespan development, ageing, thrombin, plasmin, coagulation, regeneration

Abstract

The author has discovered thrombin-plasmin system (TPS) and two processes performed by its subsystems being fundamentally opposed, internally contradictory physiological processes – biological coagulation (cyto-histo-hemocoagulation) functioning as coagulation-hypotrophic mechanism (with a reduction of all the mechanisms of trophism), therefore, its fi nal result (both in normal state and in the event of pathology) is a degenerative and dystrophic damage to cells and organs with a reduction in the number of their structures, and bioregeneration (cyto-histo-hemoregeneration) functioning as a regenerative-normotrophic mechanism, which, therefore, results in elimination of these damages, recovery of all trophic mechanisms, enhancement of cellular and intracellular regeneration with increase in the number of structures (the discovery has been registered). With the help of these two processes, TPS performs many vital functions of regulatory nature in the human body. However, the most important thing is that owing to these two processes, TPS implements a genetic program of all three stages of lifespan development of human body. This provided the author with an opportunity to substantiate two fundamentally new gerontological theories – coagulation-regenerative theory of lifespan development and coagulation- hypotrophic theory of physiological ageing of the human body. At the same time, the author has provided rationalization for regenerative-normotrophic theory of rejuvenation of the human body, since he has determined that bioregeneration is a fundamental physiological process which under certain conditions can rejuvenate the structure and functions of all organs and systems of the old human body to the level of its state at the young age, and has shown under what conditions it is possible and in what way the desired conditions could be achieved in old and senile age. The faithfulness of these gerontological theories has been confi rmed in practice – on their basis the method of consistent rejuvenation of the old human body has been established, which appeared to be very effective in animal experiments.

Downloads

Download data is not yet available.

References

Gariaiev PP. Volnovoi Genom [Wave Genome]. Мoskva. 1994:280.

Zaiko МN. Vchennia Pro Etiolohiiu Ta Patohenez. V kn.: Patolohichna Fiziolohiia [Study on Etiology and Pathogenesis]. Kyiv: Vyshcha shkolaю 1995:37–45.

Monastyrskyi VA. Koahuliatsiino-Hipotrofi chna Teoriia Fiziolohichnogo Starinnia Yak Skladova Koahuliatsiino-Reheneratsiinoi Teorii Vikovoho Rozvytku Orhanizmu [Coagulatory-and-Hypotrophic Theory of Physiologic Ageing as a Component of Coagulatory-and-Regeneration Theory of Lifespan Development]. Problemy Stareniya i Dolgoletiya. 2004;13(1):81-99.

Monastyrskyi VА. Trombin-Plazminova Systema – Odna z Osnovnykh Rehuliatornykh System Orhanizmu [Thrombin-Plasmin System is One of the Central Regulatory Body Systems]. Liha-Pres. Lviv. 2007:226.

Monastyrskyi VА. Trombin-Plazminova Systema ta Istoriia ii Vidkryttia [Thrombin-Plasmin System and the History of Its Discovery]. Krovoobih ta Hemostaz. 2008(4):5-12.

Monastyrskyi VА. Koahuliatsiini Dystrofi i – Novyi, Nedavno Vidkrytyi Vyd Dystrofi i [Coagulatory Degeneration – a New, Recently Discovered Type of Dystrophy]. Likarska Sprava. 2009(1–2):3–15.

Monastyrskyi VА, Aleksevych YІ. Sposib Omolodzhennia Orhanizmu [A Method of Human Body Rejuvenation]. Patent Ukrainy na Vynakhid No. 88576, MPK А61К38/48; Opubl.26.10.2009. Biul; 20.

Monastyrskyi VА. Starinnia ta Omolodzhennia Orhanizmu: Problemy, Yaki Vyrishuiutsia z Pozytsii Novoi Nauky – Biolohichnoi Koahulolohii [Human Body Ageing and Rejuvenation from the Perspective of the New Science – Biological Coaguology]. Lviv. LNMU. 2011:252.

Monastyrskyi VА. Starinnia ta Omolodzhennia Orhanizmu – Problemy ne Stilky Herontolohichni, Skilky Henetychno-Koahulolohichni [Human Body Ageing and Rejuvenation are Rather Genetic and Coagulatory Problems Than Gerontological]. Krovoobih ta Hemostaz. 2014(3–4):124–132.

Monastyrskyi VА. Vidkryttia, Yake Dozvolylo Stvoryty Diievyi Sposib Systemnoho Omolodzhennia Orhanizmum [Discovery That Enabled the Creation of an Effective Way of Systematic Body Rejuvenation]. Liha-Pres. Lviv. 2015:32.

Sarkisov DS. Strukturnye Osnovy Gomeostaza [Structural Foundations of Homeostasis]. V kn.: Gomeostaz. Meditsyna. Moskva.1981:256–312.

Filimonov VІ. Homeostaz і Homeokinez [Homeostasis and Homeokinesis]. V kn.: Normalna Fiziolohiia. Zdorovia. Kyiv.1994:230–236.

Frolkis VV. Stareniye i Antistareniye [Ageing and Anti-Ageing]. Mezhdunarodnyy Meditsynskiy Zhurnal. 1998; 4(4):6–11.

Monastyrsky VA. Realization of coagulation and regeneration processes is the main biological role of thrombin-plasmin system. Vidkryttya, zareyestrovane Mizhnarodnoyu Akademiyeyu informatyzaciyi. 1997;28.

Monastyrskyi V. Discovery of the trombin-plastem as one of the major regulatory systems et the organism. Eksperymental”na fiziol. ta bioxim. 2005(4-С):47-65.


Abstract views: 34
PDF Downloads: 19 PDF Downloads: 0
Published
2016-11-16
How to Cite
1.
Monastyrskyi V. REJUVENATION OF A BODY: DISCOVERY LEADING TO THE DRASTIC CHANGES OF GERONTOLOGY OPPORTUNITIES (REVIEW OF PERSONAL RESEARCHES). Proc Shevchenko Sci Soc Med Sci [Internet]. 2016Nov.16 [cited 2021Mar.5];47(2):78-9. Available from: https://mspsss.org.ua/index.php/journal/article/view/39